| Date: | July 19, 1967 |
| Location: | Near Hendersonville, North Carolina |
| Aircraft: | Boeing B-727-22 |
| Reg: | N68650 |
| Airline: | Piedmont Airlines |
| Flight No: | 22 |
| Fatalities: | 82 : 82 |
| A midair collision occurred at 6,000 feet between the B727 and a Cessna 310. The cause was the deviation from IFR clearance by the Cessna pilot and a confusing transmission by the ATC. |