Date: July 19, 1967
Location: Near Hendersonville, North Carolina
Aircraft: Boeing B-727-22
Reg: N68650
Airline: Piedmont Airlines
Flight No: 22
Fatalities: 82 : 82

A midair collision occurred at 6,000 feet between the B727 and a Cessna 310. The cause was the deviation from IFR clearance by the Cessna pilot and a confusing transmission by the ATC.